Molecular Therapy-Methods & Clinical Development

Molecular Therapy Molecular Therapy is the leading journal for research in the areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide-, protein-, oligonucleotide-, and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Molecular Therapy is dedicated to promoting the sciences in genetics, medicine, and biotechnology. Publishing important peer-reviewed research and cutting-edge reviews and commentaries, the journal continues to attract the best material in the field. Molecular Therapy''s 2015 impact factor is 6.938. Molecular Therapy — Methods & Clinical Developments The aim of Molecular Therapy—Methods & Clinical Development is to build upon the success of Molecular Therapy in publishing important peer-reviewed methods and procedures, as well as translational advances in the broad array of fields under the molecular therapy umbrella. Topics of particular interest within the journal''s scope include: Gene vector engineering and production Methods for targeted genome editing and engineering Methods and technology development for cell reprogramming and directed differentiation of pluripotent cells Methods for gene and cell vector delivery Development of biomaterials and nanoparticles for applications in gene and cell therapy and regenerative medicine Analysis of gene and cell vector biodistribution and tracking Pharmacology/toxicology studies of new and next-generation vectors Methods for cell isolation, engineering, culture, expansion, and transplantation Cell processing, storage, and banking for therapeutic application Preclinical and QC/QA assay development Translational and clinical scale-up and Good Manufacturing procedures and process development Clinical protocol development Computational and bioinformatic methods for analysis, modeling, or visualization of biological data Negotiating the regulatory approval process and obtaining such approval for clinical trials